Sphere Fluidics is an established Life Sciences Tools company, based in Babraham (UK), with a novel platform (Cyto-Mine®) that performs single cell analysis. The system is protected by a comprehensive patent portfolio and, within several hours, can automatically screen tens of millions of single cells in miniaturised aqueous pL compartments called picodroplets. The picodroplets are assayed for single cells that secrete valuable proteins (e.g. antibodies) and imaged (for monoclonality assurance) during subsequent dispensing of “hits”. Cyto-Mine® is enabling, increases throughput and reduces costs and time for biopharmaceutical discovery and development and is being adapted to single cell engineering.